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It’s possible that the genes in intestinal stem cells are linked to high fat diets and colon cancer

It's possible that the genes in intestinal stem cells are linked to high fat diets and colon cancer

New Jersey’s Rutgers University conducted a study claiming that two genes that appear to assist stem cells in the digestive tract burn fat may potentially play a role in colon cancer. According to this study, genes in the intestines of mice influence the activity of stem cells and the method in which cells consume fat. “This is crucial because researchers have shown that when there is excess dietary fat in the gut, the number of stem cells increases and boosts the vulnerability to colon cancer.” Gastroenterology reported the study’s findings. Millions of intestinal cells every day are lost in the human body, the most of which are skin cells. Consistent regeneration of the intestinal lining is supported by intestinal stem cells, however their altered roles can lead to colon cancer.

In the United States, colorectal cancer is the third most common cancer found in both men and women. A total of 101,420 Americans are expected to be diagnosed with colon cancer in 2019, according to the American Cancer Society (American Cancer Society). On a high-fat “Western” diet, intestinal stem cells have been shown to amplify in animals, which may explain the higher cancer risk. These genes were discovered to have a negative impact on mice’s intestinal stem cells, which was confirmed by the study’s researchers. Researchers at Rutgers believe that the genes can aid stem cells in the process of converting fat into energy.


A recent study from the RU found that reducing opioid cravings by practising mindfulness may be effective treatment. People who are addicted to opioids and suffer from chronic pain are said to experience less discomfort and reduced cravings if they employ mindfulness systems and opioid reliance drugs. Journal of Drug and Alcohol Dependence has published the outcomes of this study. The meditative practise of focusing on the present moment and observing one’s feelings, thoughts, and body sensations without judgement is called mindfulness.

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